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      Improving the efficiency of estrus synchronization in cows

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          Abstract

          Objective:

          This study aimed to determine the effects of biologically active substances and electrical stimulation of the uterus in cows on the effectiveness of estrus synchronization.

          Materials and Methods:

          Ninety (n = 90) Kazakh white-headed cows were synchronized with two injections of gonadotropin-releasing hormone on days 0 and 9 and prostaglandin F2α on day 7. The cows were divided into six groups and, during the protocol, treated with biologically active substances (Tetramag, Selevetum, antiseptic-stimulator Dorogov 2 fraction, groups 2, 3, and 4). Cows in groups 5 and 6 were treated with the same substances but additionally had electrical stimulation of the uterus, while cows in group 1 were left untreated and served as a control.

          Results:

          The results have shown that on Day 0, no differences were observed in E2 concentrations between the groups. However, on the 10th day, a significant disparity was noted in the E2 level among cows in group 6 compared to groups 2, 3, 4, and the control group. Conversely, no significant differences were observed between groups 5 and 6. Likewise, the fertility rate in cows from group 6 was significantly higher compared to groups 2, 3, 4, and the control group, with no significant differences between groups 5 and 6.

          Conclusion:

          It can be concluded that the utilization of electrical stimulation of the uterus and the inclusion of certain biological substances during the estrus synchronization protocol demonstrate a positive effect on the reproductive performance of beef cattle in Kazakhstan.

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          Most cited references33

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          Influence of nutrition, body condition, and metabolic status on reproduction in female beef cattle: A review

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            Intensity of estrus following an estradiol-progesterone-based ovulation synchronization protocol influences fertility outcomes.

            The objective of this study was to examine the association between increased physical activity at the moment of timed artificial insemination (AI), detected by an automated activity monitor (AAM), and fertility outcomes. This paper also investigated factors affecting estrous expression in general. A total of 1,411 AI events from 1,040 lactating Holstein cows were recorded, averaging 1.3 ± 0.6 (±standard deviation) events per cow. Activity (measured as steps/h) was monitored continuously by a leg-mounted AAM located on the rear leg of the cow. Ovulation was synchronized by a timed AI protocol based on estradiol and progesterone. Ovarian ultrasonography was performed in all cows on d -11 (AI = d 0) and in a subset of cows on d 0 (n = 588) and d 7 (n = 819) to determine the presence of a corpus luteum and follicles. The body condition score (1 to 5 scale) was assessed on d 0 and a blood sample was collected for progesterone measurement on d 7. Using the AAM, an estrus event was determined when the relative increase (RI) in physical activity of the cow exceeded 100% of the baseline activity. The physical activity was classified as strong RI (≥300% RI), moderate RI (100-300% RI), or no estrus (<100% RI). Milk production was measured daily and averaged between d -11 and 0. Pregnancy was diagnosed at 32 and 60 d post-AI and pregnancy losses were calculated. The mean RI at estrus was 328.3 ± 132.1%. Cows with strong RI had greater pregnancy per AI than those with moderate RI and those that did not express estrus (35.1 vs. 27.3 vs. 6.2%). When including only cows that successfully ovulated after timed AI, those that displayed strong intensity RI still had greater pregnancy per AI than those with moderate intensity RI or those that did not express estrus (45.1 vs. 34.8 vs. 6.2%). Cows expressing strong RI at timed AI had greater ovulation rates compared with moderate RI and cows that did not express estrus (94.9 vs. 88.2 vs. 49.5%). Furthermore, pregnancy losses were reduced in cows with strong RI compared with cows expressing moderate RI (13.9 vs. 21.7%). Cows with a strong RI at estrus were more likely to have a corpus luteum at the beginning of the protocol and had greater concentration of progesterone 7 d post-AI. Multiparous cows expressed lower RI compared with primiparous cows. Cows with lower body condition score tended to have decreased RI at estrus. No correlation between estrous expression and pre-ovulatory follicle diameter was observed. Also, no correlation was observed between milk production at AI and RI. In conclusion, strong intensity RI of estrus events at timed AI was associated with improved ovulation rates and pregnancy per AI, and reduced pregnancy losses. These results provide further evidence that measurements of estrous expression can be used to predict fertility at the time of AI and possibly be used as a tool to assist decision making strategies of reproduction programs.
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              Synchronization and Artificial Insemination Strategies in Beef Cattle

              Utilization of estrus or ovulation synchronization and fixed-timed artificial insemination (TAI) has facilitated the widespread utilization of artificial insemination (AI) and can greatly impact the economic viability of cow-calf systems by enhancing weaning weights. Implementation of TAI programs by beef producers results in limited frequency of handling cattle and elimination of the need to detect estrus. Continued use of intensive reproductive management tools such as estrus synchronization and AI will result positive changes to calving distribution, pregnancy rates, and subsequent calf value.
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                Author and article information

                Journal
                J Adv Vet Anim Res
                J Adv Vet Anim Res
                JAVAR
                Journal of Advanced Veterinary and Animal Research
                A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) (Bangladesh )
                2311-7710
                March 2024
                31 March 2024
                : 11
                : 1
                : 100-106
                Affiliations
                [1 ]Kazakh National Agrarian Research University, Almaty, Kazakhstan
                [2 ]Zhangir Khan University, Uralsk, Kazakhstan
                [3 ]Faculty of Veterinary Medicine–Skopje, Ss. Cyril and Methodius University in Skopje, Skopje, Republic of North Macedonia
                Author notes
                Contact Kumis Jumatayeva turlybekova.kumis@ 123456mail.ru Faculty of Veterinary Medicine, Kazakh National Agrarian Research University, Almaty, Republic of Kazakhstan.
                Author information
                https://orcid.org/0000-0003-4471-3910
                https://orcid.org/0000-0003-4471-3910
                https://orcid.org/0000-0003-4471-3910
                https://orcid.org/0000-0003-4471-3910
                https://orcid.org/0000-0003-4471-3910
                https://orcid.org/0000-0003-4471-3910
                Article
                10.5455/javar.2024.k753
                11055597
                38680791
                ebcec985-1001-4287-bc00-f7150f72d4f4
                Copyright: © Journal of Advanced Veterinary and Animal Research

                This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License ( http://creativecommons.org/licenses/by/4.0)

                History
                : 04 October 2023
                : 31 October 2023
                : 27 November 2023
                Categories
                Original Article

                fertility,cows,asd-2f,electrostimulation,estradiol-17β,estrus
                fertility, cows, asd-2f, electrostimulation, estradiol-17β, estrus

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