Neuroimaging characteristics of children with different subtypes of attention-deficit/hyperactivity disorder

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a common neurologic development disorder in childhood. There are significant differences in co-morbidities, behaviors, emotions, and cognitive function among patients with different subtypes of ADHD. Neuroimaging techniques (mainly MRI and EEG) provide objective and effective information for the diagnosis and intervention in children with ADHD. At present, from the perspective of the integrity and separation of brain work, combining EEG and MRI, qualitative and quantitative research has shown that there are differences in the brain structure and functional characteristics of children with different subtypes of ADHD, which is of significance to improve the diagnostic rate and treatment effect of ADHD.

Abstract

【摘要】 注意缺陷多动障碍(attention-deficit/hyperactivity disorder, ADHD)是儿童期一种常见的神经发育障碍, 不同亚型 患者在共病及其行为、情感和认知功能方面存在显著差异。以磁共振成像技术(MRI)、脑电图(EEG)为主的神经影像学技 术能为ADHD儿童诊断和干预提供客观有效的信息。从大脑工作的整体性与分离性出发, 结合EEG与MRI两类技术进 行定性、定量研究, 可发现不同亚型间ADHD儿童脑结构功能特点存在差异, 对提高ADHD诊断率, 改善治疗效果有一定 意义。