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      The Effect of Pentobarbital on Basal and Ether-Stimulated ACTH Secretion in Intact and Adrenalectomized Rats

      ,

      Neuroendocrinology

      S. Karger AG

      Ether, Pentobarbital, Adrenalectomy, Stress, ACTH

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          Abstract

          Pentobarbital in a dose of 3.5 mg/100 g b.w. did not suppress the high basal a.m. levels of plasma ACTH in adrenalectomized male rats. In both intact and adrenalectomized rats prior administration of the drug slightly depressed the rise in plasma ACTH induced by 2.5 min of ether inhalation, but this depression is of questionable statistical significance.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1975
          1975
          20 March 2008
          : 17
          : 3
          : 258-264
          Affiliations
          Division of Endocrinology, Department of Medicine, University of Oregon Medical School, Portland, Ore.
          Article
          122361 Neuroendocrinology 1975;17:258–264
          10.1159/000122361
          167319
          © 1975 S. Karger AG, Basel

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          Pages: 7
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