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      Sex differences in drug addiction and response to exercise intervention: from human to animal studies

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          Abstract

          Accumulated research supports the idea that exercise could be an option of potential prevention and treatment for drug addiction. During the past few years, there has been increased interest in investigating of sex differences in exercise and drug addiction. This demonstrates that sex-specific exercise intervention strategies may be important for preventing and treating drug addiction in men and women. However, little is known about how and why sex differences are found when doing exercise-induced interventions for drug addiction. In this review, we included both animal and human that pulled subjects from a varied age demographic, as well as neurobiological mechanisms that may highlight the sex-related differences in these potential to assess the impact of sex-specific roles in drug addiction and exercise therapies.

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          Author and article information

          Journal
          7513292
          3336
          Front Neuroendocrinol
          Front Neuroendocrinol
          Frontiers in neuroendocrinology
          0091-3022
          1095-6808
          6 August 2015
          13 July 2015
          January 2016
          01 January 2017
          : 40
          : 24-41
          Affiliations
          [1 ]Department of Sport Psychology, School of Sport Science, Shanghai University of Sport, Shanghai 200438, China
          [2 ]Shanghai Mental Health Center, Jiao Tong University School of Medicine Shanghai, China
          [3 ]Center for Hormone Advanced Science and Education, Roskamp Institute, Sarasota, FL 34243, USA
          Author notes
          [* ] Corresponding authors: Dr. Rena Li Roskamp Institute, Sarasota, FL 34243 USA rli@ 123456rfdn.org Dr. Chenglin Zhou Shanghai University of Sport, Shanghai, 200438 China Chenglin_600@ 123456126.com
          Article
          PMC4712120 PMC4712120 4712120 nihpa711480
          10.1016/j.yfrne.2015.07.001
          4712120
          26182835
          ec469e86-5119-4d03-a81f-dc5e723be848
          History
          Categories
          Article

          Sex differences,Drug addiction,Exercise,Animal and human studies,Neurobiological mechanisms

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