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      A simulation study on proton computed tomography (CT) stopping power accuracy using dual energy CT scans as benchmark.

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          Abstract

          Accurate stopping power estimation is crucial for treatment planning in proton therapy, and the uncertainties in stopping power are currently the largest contributor to the employed dose margins. Dual energy x-ray computed tomography (CT) (clinically available) and proton CT (in development) have both been proposed as methods for obtaining patient stopping power maps. The purpose of this work was to assess the accuracy of proton CT using dual energy CT scans of phantoms to establish reference accuracy levels.

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          Author and article information

          Journal
          Acta Oncol
          Acta oncologica (Stockholm, Sweden)
          Informa Healthcare
          1651-226X
          0284-186X
          2015
          : 54
          : 9
          Affiliations
          [1 ] a Department of Oncology , Aarhus University Hospital , Aarhus , Denmark.
          [2 ] b Massachussetts General Hospital and Harvard Medical School , Boston , USA.
          [3 ] c Department of Clinical Medicine , Aarhus University , Aarhus , Denmark.
          [4 ] d Department of Medical Physics , Aarhus University Hospital , Denmark.
          [5 ] e Department of Radiology , Maastricht University Medical Center (MUMC) , The Netherlands.
          [6 ] f Department of Radiation Oncology (MAASTRO) , Maastricht University Medical Center (MUMC) , Maastricht , the Netherlands.
          [7 ] g Medical Physics Unit, Department of Oncology , McGill University , Canada.
          [8 ] h Faculty of Physics, Department of Medical Physics , Ludwig-Maximilians-University , Munich , Germany.
          Article
          10.3109/0284186X.2015.1061212
          26219959
          ec495d74-9de6-4899-970a-45aec9fedf72

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