Prospective Epstein-Barr virus-related post-transplant lymphoproliferative disorder prevention program in pediatric allogeneic hematopoietic stem cell transplant: virological monitoring and first-line treatment.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

In 28 pediatric allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients, we aimed to evaluate: (i) the impact of routine Epstein-Barr virus (EBV) DNA monitoring on the development of EBV-related post-transplant lymphoproliferative disorder (EBV-PTLD); (ii) the incidence of EBV infection and the potential risk factors; and (iii) the suitability of whole blood (WB) as clinical specimen to monitor the risk of patients to develop EBV-PTLD.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Transpl Infect Dis

Title: Transplant infectious disease : an official journal of the Transplantation Society

Publisher: Wiley

ISSN (Electronic): 1399-3062

ISSN (Print): 1398-2273

Publication date (Electronic): Feb 2016

Volume: 18

Issue: 1

Affiliations

[1 ] Operative Unit of Clinical Microbiology, Laboratory of Virology, St. Orsola-Malpighi University Hospital, Bologna, Italy.

[2 ] Pediatric Oncology and Haematology Unit "Lalla Seràgnoli", Department of Pediatrics, St. Orsola-Malpighi University Hospital, Bologna, Italy.

[3 ] Department of Biomedical and Neuromotor Sciences, Unit of Hygiene and Biostatistics, University of Bologna, Bologna, Italy.

[4 ] Department of Specialised, Experimental, and Diagnostic Medicine, Operative Unit of Clinical Microbiology, Laboratory of Virology, St. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

Article

DOI: 10.1111/tid.12485

PubMed ID: 26574232

SO-VID: ec4a5865-1e90-4028-aa29-b14ddde3759c

History

Keywords: preemptive therapy,EBV-related post-transplant lymphoproliferative disorder,first-line treatment of PTLD,kinetics of EBV DNA load,pediatric allogeneic hematopoietic stem cell transplant,risk factors

Data availability:

Keywords: preemptive therapy, EBV-related post-transplant lymphoproliferative disorder, first-line treatment of PTLD, kinetics of EBV DNA load, pediatric allogeneic hematopoietic stem cell transplant, risk factors

Prospective Epstein-Barr virus-related post-transplant lymphoproliferative disorder prevention program in pediatric allogeneic hematopoietic stem cell transplant: virological monitoring and first-line treatment.

Read this article at

Abstract

Related collections

Cures Within Reach: Autoimmune Lymphoproliferative Syndrome (ALPS)

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 298

Cited by 5