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      Erratum to: A review on Lactococcus lactis: from food to factory

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          Abstract

          Erratum to: Microb Cell Fact (2017) 16:55 DOI 10.1186/s12934-017-0669-x Following the publication of this article [1], it was brought to our attention that unfortunately there is an error in the Abstract. The Abstract currently reads: “…This have made L. lactis a desirable and promising host on par with other well established model bacterial or yeast systems such as Escherichia coli, Salmonella cerevisiae and Bacillus subtilis…”. This should instead read: “…This have made L. lactis a desirable and promising host on par with other well established model bacterial or yeast systems such as Escherichia coli, Saccharomyces cerevisiae and Bacillus subtilis…”.

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          A review on Lactococcus lactis: from food to factory

          Lactococcus lactis has progressed a long way since its discovery and initial use in dairy product fermentation, to its present biotechnological applications in genetic engineering for the production of various recombinant proteins and metabolites that transcends the heterologous species barrier. Key desirable features of this gram-positive lactic acid non-colonizing gut bacteria include its generally recognized as safe (GRAS) status, probiotic properties, the absence of inclusion bodies and endotoxins, surface display and extracellular secretion technology, and a diverse selection of cloning and inducible expression vectors. This have made L. lactis a desirable and promising host on par with other well established model bacterial or yeast systems such as Escherichia coli, Salmonella cerevisiae and Bacillus subtilis. In this article, we review recent technological advancements, challenges, future prospects and current diversified examples on the use of L. lactis as a microbial cell factory. Additionally, we will also highlight latest medical-based applications involving whole-cell L. lactis as a live delivery vector for the administration of therapeutics against both communicable and non-communicable diseases.
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            Author and article information

            Contributors
            adelene@upm.edu.my
            Journal
            Microb Cell Fact
            Microb. Cell Fact
            Microbial Cell Factories
            BioMed Central (London )
            1475-2859
            9 August 2017
            9 August 2017
            2017
            : 16
            : 139
            Affiliations
            [1 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Department of Microbiology, Faculty of Biotechnology & Biomolecular Sciences, , University Putra Malaysia, ; 43400 Serdang, Selangor Malaysia
            [2 ]GRID grid.444472.5, Functional Food Research Group, Department of Biotechnology, Faculty of Applied Sciences, , UCSI University, ; Kuala Lumpur, Malaysia
            [3 ]GRID grid.261834.a, , Perdana University-Royal College of Surgeons in Ireland, Perdana University, ; Block B and D, MAEPS Building, MARDI Complex, Jalan MAEPS Perdana, 43400 Serdang, Selangor Malaysia
            [4 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Department of Cell & Molecular Biology, Faculty of Biotechnology & Biomolecular Sciences, , University Putra Malaysia, ; Serdang, Selangor Malaysia
            Article
            754
            10.1186/s12934-017-0754-1
            5549287
            28793898
            ec57525a-ca11-4bc2-ab5c-04f109369124
            © The Author(s) 2017

            Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

            History
            : 4 August 2017
            : 4 August 2017
            Categories
            Erratum
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            © The Author(s) 2017

            Biotechnology
            Biotechnology

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