The New Jersey serotype of vesicular stomatitis virus (VSNJ) is enzootic on Ossabaw Island, Georgia. Lutzomyia shannoni is the only phlebotomine sand fly present on the island and there is strong evidence that it is a vector of the virus at this site. This overview summarizes the studies that have been done on the island, reviews the evidence which confirms that L. shannoni is a biological vector of VSNJ, and discusses remaining unknown aspects of the epizootiology of VSNJ.