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      Thromboinflammatory response in SARS-CoV-2 sepsis

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          Abstract

          Viral sepsis is rare, and its real incidence is not known. SARS-CoV-2 infection causes the release of a significant amount of pro-inflammatory cytokines that aggravates interstitial pneumonia and evolves in viral sepsis with prominent hypercoagulability. We believe it is useful and advisable to establish early immunomodulator therapy and the prophylaxis anticoagulant therapy should be rethought.

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          Author and article information

          Journal
          Medico-Legal Journal
          Med Leg J
          SAGE Publications
          0025-8172
          2042-1834
          July 2020
          June 03 2020
          July 2020
          : 88
          : 2
          : 78-80
          Affiliations
          [1 ]Department of Surgical Pathology, Medical, Molecular and Critical Area, Institute of Legal Medicine, University of Pisa, Pisa, Italy
          [2 ]Gemelli IRCCS Research Hospital, Fondazione Policlinico Universitario A. Rome, Italy
          [3 ]Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy
          Article
          10.1177/0025817220926915
          32490726
          ec9a4ec1-7e45-4f37-aa71-4c6f57e3f859
          © 2020

          http://journals.sagepub.com/page/policies/text-and-data-mining-license

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