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      Geographic Trends in Opioid Overdoses in the US From 1999 to 2020

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          Abstract

          This cross-sectional study examines changes in rates of opioid-involved overdose deaths from 1999 to 2020 in US counties categorized from most urban to most rural.

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          The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis

          This review provides an update on recently published literature on the rise of illicit fentanyls, risks for overdose, combinations with other substances, e.g. stimulants, consequences, and treatment.
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            The triple wave epidemic: Supply and demand drivers of the US opioid overdose crisis

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              Management of opioid use disorder in the USA: present status and future directions

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                Author and article information

                Journal
                JAMA Netw Open
                JAMA Netw Open
                JAMA Network Open
                American Medical Association
                2574-3805
                28 July 2022
                July 2022
                28 July 2022
                : 5
                : 7
                : e2223631
                Affiliations
                [1 ]Department of Emergency Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
                [2 ]Feinberg School of Medicine, Northwestern University, Chicago, Illinois
                [3 ]Buehler Center for Health Policy and Economics, Chicago, Illinois
                [4 ]Department of Agricultural Economics, University of Florida, Gainesville
                [5 ]Center for Health Informatics, Yale School of Medicine, New Haven, Connecticut
                Author notes
                Article Information
                Accepted for Publication: June 4, 2022.
                Published: July 28, 2022. doi:10.1001/jamanetworkopen.2022.23631
                Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2022 Post LA et al. JAMA Network Open.
                Corresponding Author: Lori Ann Post, PhD, Buehler Center for Health Policy and Economics, Feinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL 60611 ( lori.post@ 123456northwestern.edu ).
                Author Contributions: Drs Post and Mason had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
                Concept and design: Post, Moss, Brandt, Quan, Mason.
                Acquisition, analysis, or interpretation of data: Post, Lundberg, Quan, Han, Mason.
                Drafting of the manuscript: Post, Lundberg, Quan, Mason.
                Critical revision of the manuscript for important intellectual content: All authors.
                Statistical analysis: Post, Lundberg, Moss, Quan, Han, Mason.
                Obtained funding: Post.
                Administrative, technical, or material support: Brandt, Quan, Mason.
                Conflict of Interest Disclosures: None reported.
                Funding/Support: This study was funded in part by grant 2019-67023-29347 from the USDA (Drs Post and Moss) and grant UL1TR001422 from the National Center for Advancing Translational Sciences, NIH and Northwestern University Clinical and Translational Sciences Institute (Dr Post).
                Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
                Article
                zld220155
                10.1001/jamanetworkopen.2022.23631
                9335141
                35900768
                ecb5bdd8-cf06-472e-bbb1-19457a4be5b0
                Copyright 2022 Post LA et al. JAMA Network Open.

                This is an open access article distributed under the terms of the CC-BY License.

                History
                : 7 April 2022
                : 4 June 2022
                Categories
                Research
                Research Letter
                Online Only
                Substance Use and Addiction

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