Concentration-dependent effect of sodium hypochlorite on stem cells of apical papilla survival and differentiation.

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Abstract

Intracanal disinfection is a crucial step in regenerative endodontic procedures. Most published cases suggest the use of sodium hypochlorite (NaOCl) as the primary irrigant. However, the effect of clinically used concentrations of NaOCl on the survival and differentiation of stem cells is largely unknown. In this study, we tested the effect of various concentrations of NaOCl on the stem cells of the apical papilla (SCAPs) survival and dentin sialophosphoprotein (DSPP) expression.

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Journal

Journal ID (iso-abbrev): J Endod

Title: Journal of endodontics

ISSN (Electronic): 1878-3554

ISSN (Print): 0099-2399

Publication date (Electronic): Jan 2014

Volume: 40

Issue: 1

Affiliations

[1 ] Department of Endodontics, University of Texas Health Science Center at San Antonio, Texas.

[2 ] Department of Restorative Dentistry, Piracicaba School of Dentistry, State University of Campinas, São Paulo, Brazil.

[3 ] Department of Biomedical Engineering, University of Texas, Austin, Texas.

[4 ] Department of Endodontics, University of Texas Health Science Center at San Antonio, Texas. Electronic address: Diogenes@uthscsa.edu.

Article

Publisher Item ID: S0099-2399(13)00647-X

DOI: 10.1016/j.joen.2013.07.026

PubMed ID: 24331991

SO-VID: ecc1fa83-89ac-44f1-9b7f-0ea3b8059473

History

Keywords: Dentin conditioning,EDTA,dentin sialophosphoprotein,gene expression,irrigant,regenerative endodontics,sodium hypochlorite,stem cells of apical papilla,survival,viability

Data availability:

Keywords: Dentin conditioning, EDTA, dentin sialophosphoprotein, gene expression, irrigant, regenerative endodontics, sodium hypochlorite, stem cells of apical papilla, survival, viability

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