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Association between hippuric acid and left ventricular hypertrophy in maintenance hemodialysis patients
Teng-Hung Yu ,
Wei-Hua Tang ,
Yung-Chuan Lu ,
Chao-Ping Wang ,
Wei-Chin Hung ,
Cheng-Ching Wu ,
I-Ting Tsai ,
Fu-Mei Chung ,
Jer-Yiing Houng ,
Wen-Chun Lan ,
Yau-Jiunn Lee
September 2018
September 2018
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Abstract
<p class="first" id="d3612023e191">Left ventricular hypertrophy (LVH) is one of the
most common cardiac abnormalities
in patients with end-stage renal disease. Hippuric acid (HA), a harmful uremic toxin,
is known to be elevated in patients with uremia, and serum HA levels are associated
with neurological symptoms, metabolic acidosis, and accelerated renal damage associated
with chronic kidney disease. However, the pathophysiological role of HA in patients
with uremia remains unclear. We investigated the association between serum HA levels
and echocardiographic measurements in patients undergoing hemodialysis (HD) treatment.
</p>