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      A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark

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          Abstract

          Along with three known drimanes, polygodial. 1-beta-(p-methoxycinnamoyl) polygodial and mukaadial, the sesquiterpene drimane named drimanial was isolated from the bark of Drimys winteri (Winteraceae). Its structure was elucidated based on spectroscopic evidence. Drimanial exhibited antinociceptive action against acetic acid induced pain, being about 3-fold less active than polygodial.

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          Author and article information

          Journal
          Phytochemistry
          Phytochemistry
          Elsevier BV
          00319422
          May 2001
          May 2001
          : 57
          : 1
          : 103-107
          Article
          10.1016/S0031-9422(00)00515-X
          11336250
          ecd0131f-d0af-459a-af7f-037b6652dced
          © 2001

          https://www.elsevier.com/tdm/userlicense/1.0/

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