Increased choroidal mast cells and their degranulation in age-related macular degeneration.

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Abstract

Inflammation has been implicated in age-related macular degeneration (AMD). This study investigates the association of mast cells (MCs), a resident choroidal inflammatory cell, with pathological changes in AMD.

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Journal

Journal ID (iso-abbrev): Br J Ophthalmol

Title: The British journal of ophthalmology

Publisher: BMJ

ISSN (Electronic): 1468-2079

ISSN (Print): 0007-1161

Publication date (Electronic): May 2016

Volume: 100

Issue: 5

Affiliations

[1 ] Department of Ophthalmology, Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore, Maryland, USA.

[2 ] Biostatistics Consulting Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

[3 ] Hoover Low Vision Rehabilitation Services, Greater Baltimore Medical Center, Baltimore, Maryland, USA Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.

[4 ] Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Boston, Massachusetts, USA Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts, USA.

Article

Publisher Item ID: bjophthalmol-2015-308290 Mid ID: NIHMS795190

DOI: 10.1136/bjophthalmol-2015-308290

PMC ID: 4913697

PubMed ID: 26931413

SO-VID: eceaee0f-5e8e-4bfe-9701-038866931373

History

Keywords: Choroid,Inflammation,Macula,Neovascularisation,Pathology

Data availability:

Keywords: Choroid, Inflammation, Macula, Neovascularisation, Pathology

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