Greta Simionato:
ORCID: https://orcid.org/0000-0001-5452-2275
Role: Data curationRole: Formal analysisRole: MethodologyRole: ValidationRole: VisualizationRole:
Writing – original draftRole: Writing – review & editing
Konrad Hinkelmann: Role: Data curationRole: Formal analysisRole: MethodologyRole: ResourcesRole: SoftwareRole:
ValidationRole: VisualizationRole: Writing – review & editing
Revaz Chachanidze:
ORCID: https://orcid.org/0000-0001-6748-6197
Role: Data curationRole: Formal analysisRole: MethodologyRole: Writing – original
draftRole: Writing – review & editing
Paola Bianchi:
ORCID: https://orcid.org/0000-0001-5976-5233
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Elisa Fermo:
ORCID: https://orcid.org/0000-0003-2812-8711
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Richard van Wijk: Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Marc Leonetti: Role: Writing – review & editing
Christian Wagner:
ORCID: https://orcid.org/0000-0001-7788-4594
Role: Funding acquisitionRole: ResourcesRole: Writing – review & editing
Lars Kaestner: Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
ResourcesRole: SupervisionRole: Writing – review & editing
Stephan Quint:
ORCID: https://orcid.org/0000-0003-4412-7559
Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: MethodologyRole:
Project administrationRole: ResourcesRole: SupervisionRole: Writing – review & editing
Dina Schneidman-Duhovny: Role: Editor
Journal ID (nlm-ta): PLoS Comput Biol
Journal ID (iso-abbrev): PLoS Comput Biol
Journal ID (publisher-id): plos
Journal ID (pmc): ploscomp
Title:
PLoS Computational Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-734X
ISSN
(Electronic):
1553-7358
Publication date Collection:
May
2021
Publication date
(Electronic):
13
May
2021
Volume: 17
Issue: 5
Electronic Location Identifier: e1008934
Affiliations
[1
]
Department of Experimental Physics, Saarland University, Campus E2.6, Saarbrücken,
Germany
[2
]
Institute for Clinical and Experimental Surgery, Saarland University, Campus University
Hospital, Homburg, Germany
[3
]
CNRS, University Grenoble Alpes, Grenoble INP, LRP, Grenoble, France
[4
]
Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy
[5
]
Department of Clinical Chemistry & Haematology, University Medical Center Utrecht,
Utrecht, The Netherlands
[6
]
Physics and Materials Science Research Unit, University of Luxembourg, Luxembourg
City, Luxembourg
[7
]
Theoretical Medicine and Biosciences, Saarland University, Campus University Hospital,
Homburg, Germany
[8
]
Cysmic GmbH, Saarland University, Saarbrücken, Germany
Hebrew University of Jerusalem, ISRAEL
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PCOMPBIOL-D-20-02103
DOI: 10.1371/journal.pcbi.1008934
PMC ID: 8118337
PubMed ID: 33983926
SO-VID: ed08daad-282a-4d10-9395-d4e061c6fe16
Copyright © © 2021 Simionato et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: Deutsche Forschungsgemeinschaft
Award ID: FOR 2688
Award Recipient
:
ORCID: https://orcid.org/0000-0001-5452-2275
Greta Simionato
Funded by: Deutsche Forschungsgemeinschaft
Award ID: FOR 2688
Award Recipient
:
Lars Kaestner
Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
Award ID: FOR 2688
Award Recipient
:
ORCID: https://orcid.org/0000-0001-7788-4594
Christian Wagner
Funded by: funder-id http://dx.doi.org/10.13039/100010661, Horizon 2020 Framework Programme;
Award ID: 860436-EVIDENCE
Award Recipient
:
Lars Kaestner
Funded by: funder-id http://dx.doi.org/10.13039/100010661, Horizon 2020 Framework Programme;
Award ID: 860436-EVIDENCE
Award Recipient
:
Richard van Wijk
Funded by: funder-id http://dx.doi.org/10.13039/100010661, Horizon 2020 Framework Programme;
Award ID: 860436-EVIDENCE
Award Recipient
:
ORCID: https://orcid.org/0000-0001-7788-4594
Christian Wagner
Funded by: funder-id http://dx.doi.org/10.13039/100010661, Horizon 2020 Framework Programme;
Award ID: 860436-EVIDENCE
Award Recipient
:
ORCID: https://orcid.org/0000-0003-4412-7559
Stephan Quint
Funded by: funder-id http://dx.doi.org/10.13039/501100001663, Volkswagen Foundation;
Award ID: Experiment!
Award Recipient
:
Lars Kaestner
Funded by: funder-id http://dx.doi.org/10.13039/501100001663, Volkswagen Foundation;
Award ID: Experiment!
Award Recipient
:
ORCID: https://orcid.org/0000-0003-4412-7559
Stephan Quint
G.S., L.K., and C.W. received funding from Deutsche Forschungsgemeinschaft (DFG),
https://www.dfg.de/, in the framework of the research unit FOR 2688. L.K., R.W., C.W., and S.Q are funded
by the European Union’s Horizon 2020 Research and Innovation Programme,
https://ec.europa.eu/research/mariecurieactions/node_en, under the Marie Sklodowska-Curie grant agreement no 860436 – EVIDENCE. L.K., and
S.Q. are funded by Volkswagenstiftung, grant scheme “Experiment!”,
https://www.volkswagenstiftung.de/unsere-foerderung/unser-foerderangebot-im-ueberblick/experiment. Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) and Saarland University
granted the fundings for Open Access Publishing. The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Computer and Information Sciences
Subject:
Artificial Intelligence
Subject:
Artificial Neural Networks
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Computational Neuroscience
Subject:
Artificial Neural Networks
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Computational Neuroscience
Subject:
Artificial Neural Networks
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Blood
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Blood
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Blood
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
Red Blood Cells
Subject:
Spherocytes
Subject:
Research and Analysis Methods
Subject:
Microscopy
Subject:
Light Microscopy
Subject:
Confocal Microscopy
Subject:
Physical Sciences
Subject:
Mathematics
Subject:
Numerical Analysis
Subject:
Interpolation
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Human Genetics
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Engineering and Technology
Subject:
Industrial Engineering
Subject:
Control Engineering
Subject:
Automation