- Record: found
- Abstract: found
- Article: not found
[Hypoxia, HIF1alpha and estrogen receptor].
Read this article at
ScienceOpenPubMed
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
The estrogen receptor plays an important role in the development of hormone-dependent breast cancer. Experimental and clinical studies showed that hypoxia was involved in tumor progression and in the resistance to anticancer agents. The scope of this review is to summarize recent observations on these two signaling pathways and to show their importance and possible interaction in the development of hormone-dependent breast cancer.