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      Opportunities and challenges in antiparasitic drug discovery.

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          Abstract

          New antiparasitic drugs are urgently needed to treat and control diseases such as malaria, leishmaniasis, sleeping sickness and filariasis, which affect millions of people each year. However, because the majority of those infected live in countries in which the prospects of any financial return on investment are too low to support market-driven drug discovery and development, alternative approaches are needed. In this article, challenges and opportunities for antiparasitic drug discovery are considered, highlighting some of the progress that has been made in recent years, partly through scientific advances, but also by more effective partnership between the public and private sectors.

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          Author and article information

          Journal
          Nat Rev Drug Discov
          Nature reviews. Drug discovery
          Springer Science and Business Media LLC
          1474-1776
          1474-1776
          Sep 2005
          : 4
          : 9
          Affiliations
          [1 ] TDR (the UNICEF/UNDP/World Bank/WHO/Special Programme for Research and Training in Tropical Diseases), Geneva 1211, Switzerland.
          Article
          nrd1824
          10.1038/nrd1824
          16138106
          ed4eaa76-0433-4a97-9ba4-f2f4fade62cf
          History

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