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      Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy.

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          Abstract

          To evaluate the efficacy and safety of the epidermal growth factor receptor-directed monoclonal antibody cetuximab administered as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN) who experience disease progression on platinum therapy.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          1527-7755
          0732-183X
          Jun 01 2007
          : 25
          : 16
          Affiliations
          [1 ] Department of Medical Oncology, University Hospital Antwerpen, Edegem, Belgium. Jan.B.Vermorken@uza.be
          Article
          25/16/2171
          10.1200/JCO.2006.06.7447
          17538161
          edf621c8-d36a-4385-88be-701bd4a887c1
          History

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