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      A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS)

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          Abstract

          Background

          Polycystic ovary syndrome (PCOS) is a frequent medical condition characterized by both metabolic and reproductive disorders. Different pharmaceutical treatments have been proposed for PCOS. However, side effects of long-term treatments and their probable low efficacy have made complementary and alternative treatments a valuable option. Recent reports have indicated the increased use of complementary treatments. Herbal medicine, as part of complementary medicine, was find introduced in traditional Persian and Chinese medicine. Medicinal herbs have used for a long time in the treatment of gynecological and infertility problems of PCOS patients. In this study, we aimed to review herbal medicines used for PCOS worldwide.

          Methods

          PubMed, Embase, Cochrane, and Scopus databases were searched for clinical trials and Randomized Controlled Trials based on related keywords. Data were collected from 1990 to 2019.

          Results

          According to a multitude of studies, a wide spectrum of herbs can be used to improve various aspects of PCOS. Herbs such as Cinnamomum verum, Trigonella foenum-graecum L ., and Vitex agnus-castus can impact on menstrual and ovulatory dysfunctions, obesity, insulin resistance, lipid-metabolism dysfunction, and androgen excess-related conditions.

          Conclusion

          Some plants as natural remedies may have beneficial effects on improving different aspects of PCOS; but further studies are needed to investigate their mechanisms and safety.

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          Author and article information

          Contributors
          +989141593633 , modir7060@yahoo.com
          Journal
          Daru
          Daru
          DARU Journal of Pharmaceutical Sciences
          Springer International Publishing (Cham )
          1560-8115
          2008-2231
          18 November 2019
          December 2019
          : 27
          : 2
          : 863-877
          Affiliations
          [1 ] GRID grid.411426.4, ISNI 0000 0004 0611 7226, Department of Obstetrics and Gynecology, School of Medicine, , Ardabil University of Medical Sciences, ; Ardabil, Iran
          [2 ] GRID grid.411426.4, ISNI 0000 0004 0611 7226, Pharmaceutical Sciences Research Center, , Ardabil University of Medical Sciences, ; Ardabil, Iran
          [3 ] GRID grid.411426.4, ISNI 0000 0004 0611 7226, Students Research Committee, School of Medicine, , Ardabil University of Medical Sciences, ; Ardabil, Iran
          Article
          PMC6895349 PMC6895349 6895349 312
          10.1007/s40199-019-00312-0
          6895349
          31741280
          © Springer Nature Switzerland AG 2019
          Categories
          Review Article
          Custom metadata
          © Springer Nature Switzerland AG 2019

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