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      Adenocarcinoma mucinoso gigante de glándula submandibular: presentación de un caso extremadamente infrecuente Translated title: Giant mucinous adenocarcinoma of the submandibular gland. Report on an extremely rare case

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          Abstract

          RESUMEN El adenocarcinoma mucinoso es una entidad patológica poco frecuente dentro de las neoplasias que afectan a las glándulas salivales. Se presenta el caso de una paciente de 89 años con antecedentes de un aumento de volumen en el cuello. Al examen físico se constató una tumoración que abarcaba toda la región cervical derecha y se extendía desde la región submandibular hasta la región clavipectoral homolateral. El estudio histopatológico confirmó un adenocarcinoma mucinoso de bajo grado. Se efectuó una disección del cuello extendida a piel y luego se reconstruyó la zona con un colgajo miocutáneo de músculo pectoral mayor, debido al defecto generado por la eliminación del gran volumen tumoral. En conclusión, se presenta un caso extremadamente infrecuente de adenocarcinoma mucinoso de glándula submandibular de tamaño gigante.

          Translated abstract

          ABSTRACT Mucinous Adenocarcinoma is a rare pathological entity within neoplasms that affect the salivary glands. The case of an 89-year-old female patient with a history of increased volume in the neck is presented. Physical examination revealed a tumor that covered the entire right cervical region and extended from the submandibular region to the ipsilateral clavipectoral region. The histopathological study confirmed a low grade Mucinous Adenocarcinoma. A neck dissection extended to the skin was performed and then the area was reconstructed with a myocutaneous flap from the pectoralis major muscle due to the defect generated by the removal of the large tumor volume. In conclusion, an extremely rare giant-sized mucinous adenocarcinoma of the submandibular gland is presented.

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          Most cited references10

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          Salivary Mucinous Adenocarcinoma Is a Histologically Diverse Single Entity With Recurrent AKT1 E17K Mutations : Clinicopathologic and Molecular Characterization With Proposal for a Unified Classification

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            2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors

            Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.
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              Updated WHO nomenclature of head and neck lesions and associated imaging findings

              This article reviews the imaging features of head and neck lesions with updated 2017 World Health Organization (WHO) nomenclature. The major WHO changes include refined terminology of existing entities, descriptions of new tumor types, elimination of defunct categories, and updated biological characterization of various tumor types. In particular, the updates pertaining to the following conditions will be reviewed: tumors of the oral cavity and oropharynx, including HPV-positive or HPV-negative squamous cell carcinoma, small cell carcinoma; tumors of the hypopharynx, larynx, trachea, and parapharyngeal space, including nomenclature revisions for laryngeal neuroendocrine tumors; tumors of the nasal cavity and paranasal sinuses including newly added entities such as NUT carcinoma and biphenotypic sinonasal sarcoma; odontogenic and maxillofacial bone tumors, including the reversal of terminology for certain cystic lesions; tumors of the salivary glands, including updated terminology related to high-grade transformation and polymorphous adenocarcinomas tumors; temporal bone lesions including modifications of the nomenclature and classification criteria; tumor-like lesions of the neck and lymph nodes, with a discussion encompassing developmental cysts, metastases of unknown primary, and heterotopia-associated neoplasia; and mucosal melanoma. Familiarity with the proper WHO terminology for conditions that might be mentioned in differential diagnoses and a general understanding of the behavior of head and neck lesions can help optimize imaging assessment and reporting.
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                Author and article information

                Journal
                maxi
                Revista Española de Cirugía Oral y Maxilofacial
                Rev Esp Cirug Oral y Maxilofac
                Sociedad Española de Cirugía Oral y Maxilofacial y de Cabeza y Cuello (Madrid, Madrid, Spain )
                1130-0558
                2173-9161
                March 2023
                : 45
                : 1
                : 37-40
                Affiliations
                [1] Villa Clara-Santa Clara orgnameHospital Provincial Universitario Arnaldo Milián Castro orgdiv1Servicio de Cirugía Maxilofacial Cuba
                Article
                S1130-05582023000100006 S1130-0558(23)04500100006
                10.20986/recom.2023.1429/2023
                ee2e81c4-3bf3-4f88-9209-697fda51aa8c

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 15 April 2023
                : 19 February 2023
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 10, Pages: 4
                Product

                SciELO Spain

                Categories
                Casos Clínicos

                Neoplasia,submandibular gland,mucinous adenocarcinoma,glándula submandibular,adenocarcinoma mucinoso

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