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Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins.
Jan 2000
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Abstract
Twin concordance data for rheumatoid arthritis (RA) on their own provide only limited insight into the relative genetic and environmental contribution to the disease. We applied quantitative genetic methods to assess the heritability of RA and to examine for evidence of differences in the genetic contribution according to sex, age, and clinical disease characteristics.