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      Mixing Optimization in Grooved Serpentine Microchannels

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          Abstract

          Computational fluid dynamics modeling at Reynolds numbers ranging from 10 to 100 was used to characterize the performance of a new type of micromixer employing a serpentine channel with a grooved surface. The new topology exploits the overlap between the typical Dean flows present in curved channels due to the centrifugal forces experienced by the fluids, and the helical flows induced by slanted groove-ridge patterns with respect to the direction of the flow. The resulting flows are complex, with multiple vortices and saddle points, leading to enhanced mixing across the section of the channel. The optimization of the mixers with respect to the inner radius of curvature ( R in ) of the serpentine channel identifies the designs in which the mixing index quality is both high ( M > 0.95) and independent of the Reynolds number across all the values investigated.

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          Most cited references57

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          Chaotic mixer for microchannels.

          It is difficult to mix solutions in microchannels. Under typical operating conditions, flows in these channels are laminar-the spontaneous fluctuations of velocity that tend to homogenize fluids in turbulent flows are absent, and molecular diffusion across the channels is slow. We present a passive method for mixing streams of steady pressure-driven flows in microchannels at low Reynolds number. Using this method, the length of the channel required for mixing grows only logarithmically with the Péclet number, and hydrodynamic dispersion along the channel is reduced relative to that in a simple, smooth channel. This method uses bas-relief structures on the floor of the channel that are easily fabricated with commonly used methods of planar lithography.
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            3D printed microfluidic devices: enablers and barriers.

            3D printing has the potential to significantly change the field of microfluidics. The ability to fabricate a complete microfluidic device in a single step from a computer model has obvious attractions, but it is the ability to create truly three dimensional structures that will provide new microfluidic capability that is challenging, if not impossible to make with existing approaches. This critical review covers the current state of 3D printing for microfluidics, focusing on the four most frequently used printing approaches: inkjet (i3DP), stereolithography (SLA), two photon polymerisation (2PP) and extrusion printing (focusing on fused deposition modeling). It discusses current achievements and limitations, and opportunities for advancement to reach 3D printing's full potential.
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              Micromixers—a review

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                Author and article information

                Journal
                Micromachines (Basel)
                Micromachines (Basel)
                micromachines
                Micromachines
                MDPI
                2072-666X
                04 January 2020
                January 2020
                : 11
                : 1
                : 61
                Affiliations
                [1 ]Department of Physics, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH 44236, USA; t.d.rhoades@ 123456vikes.csuohio.edu
                [2 ]Department of Chemical and Biomedical Engineering, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH 44236, USA; c.kothapalli@ 123456csuohio.edu
                Author notes
                [* ]Correspondence: p.fodor@ 123456csuohio.edu ; Tel.: +1-216-523-7520
                Author information
                https://orcid.org/0000-0001-8450-0640
                Article
                micromachines-11-00061
                10.3390/mi11010061
                7019475
                31947897
                ee3db577-715a-4031-9e63-237c844d14c7
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 06 December 2019
                : 02 January 2020
                Categories
                Article

                passive micromixers,dean flows and mixers,serpentine channels,staggered herring bone (shb) mixers,mixing index

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