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      Neoplasias hepáticas malignas: Hepatocarcinoma: papel de la biopsia hepática, estudios de inmunohistoquímica y otros aspectos importantes Translated title: Malignant Hepatic Neoplasms: Hepatocellular carcinoma: the roles of liver biopsies and immunohistochemical studies and other important issues


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          Continuamos con la revisión de los tumores hepáticos. Nos referiremos a los tumores hepáticos primarios malignos más frecuentes. Tal como lo mencionamos anteriormente, los tumores malignos hepatobiliares son un espectro de tumores invasivos que reciben su nombre dependiendo de su célula de origen. De acuerdo con la Agencia Internacional para el Estudio del Cáncer (IARC), los tumores hepáticos malignos constituyen la segunda causa de muerte en el mundo, con aproximadamente 745 000 muertes/año (1). Al igual que en el artículo anterior, el objetivo es identificar aquellos aspectos más relevantes de estas neoplasias, en especial los hallazgos morfológicos que generan mayor problema diagnóstico en la utilidad de los estudios de inmunohistoquímica y sus diagnósticos diferenciales. La primera parte de esta revisión se centrará en el hepatocarcinoma, el más frecuente de los tumores hepáticos epiteliales malignos, algunas de sus variantes y sus lesiones precursoras. También en el controvertido papel de la biopsia hepática para su diagnóstico

          Translated abstract

          We continue with our review of liver tumors in which we will refer to the most common primary malignant liver tumors. As mentioned previously, hepatobiliary malignancies are a spectrum of invasive tumors whose names depend on their origins. According to the International Agency for Research on Cancer (IARC), malignant liver tumors are the second leading cause of death worldwide with approximately 745,000 deaths/year. (1) As in the previous article, the aim here will be to identify the most relevant aspects of these neoplasms. In particular we will look at morphological findings that generate major diagnostic problems and at the usefulness of immunohistochemical studies and their differential diagnoses. Hepatic carcinoma, the most frequent malignant epithelial tumor of the liver is the focus of the first part of this review. We will look at some of its variants and its precursor lesions, and at the controversial role of liver biopsies for diagnosis

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          Most cited references 48

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                Author and article information

                Revista colombiana de Gastroenterología
                Rev. colomb. Gastroenterol.
                Asociación Colombiana de Gastroenterología (Bogotá, , Colombia )
                June 2015
                : 30
                : 2
                : 232-242
                [01] Bogotá orgnameHospital Universitario Fundación Santa Fe de Bogotá orgdiv1Sección Anatomía Patológica Colombia
                S0120-99572015000200014 S0120-9957(15)03000214

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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