9
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Cocaine addiction: psychology and neurophysiology.

      Science (New York, N.Y.)
      Cocaine, adverse effects, Humans, Models, Psychological, Nervous System, physiopathology, Substance Withdrawal Syndrome, psychology, Substance-Related Disorders

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Cocaine was considered incapable of producing dependence in 1980 but was recently proclaimed the drug of greatest national health concern. Recent clinical and preclinical investigations demonstrate that cocaine produces unique abuse and withdrawal patterns that differ from those of other major abused drugs and suggest that long-term cocaine abuse produces neurophysiological alterations in specific systems in the central nervous system that regulate the capacity to experience pleasure. It will be necessary to develop clinically pertinent research models before these findings can be considered definitive, but these evolving ideas have already led to applications of promising experimental treatments for cocaine abuse.

          Related collections

          Author and article information

          Journal
          2011738
          10.1126/science.2011738

          Chemistry
          Cocaine,adverse effects,Humans,Models, Psychological,Nervous System,physiopathology,Substance Withdrawal Syndrome,psychology,Substance-Related Disorders

          Comments

          Comment on this article