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      Wound healing--aiming for perfect skin regeneration.

      1
      Science (New York, N.Y.)
      American Association for the Advancement of Science (AAAS)

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          Abstract

          The healing of an adult skin wound is a complex process requiring the collaborative efforts of many different tissues and cell lineages. The behavior of each of the contributing cell types during the phases of proliferation, migration, matrix synthesis, and contraction, as well as the growth factor and matrix signals present at a wound site, are now roughly understood. Details of how these signals control wound cell activities are beginning to emerge, and studies of healing in embryos have begun to show how the normal adult repair process might be readjusted to make it less like patching up and more like regeneration.

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          Author and article information

          Journal
          Science
          Science (New York, N.Y.)
          American Association for the Advancement of Science (AAAS)
          0036-8075
          0036-8075
          Apr 04 1997
          : 276
          : 5309
          Affiliations
          [1 ] Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. paul.martin@ucl.ac.uk
          Article
          10.1126/science.276.5309.75
          9082989
          eed1ea47-0c18-4f86-af59-a8a0395bb1e6
          History

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