Sensitivity, Specificity, and Predictors of Positive 68Ga-Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer: A Systematic Review and Meta-analysis.

Perera, Marlon; Papa, Nathan; Christidis, Daniel; Wetherell, David; Hofman, Michael S.; Murphy, Declan G M; Bolton, Damien; Lawrentschuk, Nathan

doi:10.1016/j.eururo.2016.06.021

Record: found
Abstract: found
Article: not found

Sensitivity, Specificity, and Predictors of Positive 68Ga-Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer: A Systematic Review and Meta-analysis.

Author(s): Marlon Perera, Nathan Papa, Daniel Christidis, David Wetherell, Michael Hofman, Declan Murphy, Damien Bolton, Nathan Lawrentschuk

Publication date: 2016-12-01

Journal: European Urology

Publisher: Elsevier BV

Keywords: Metastases, Biochemical recurrence, Imaging, Positron emission tomography, Prostate cancer, Prostate-specific antigen, Prostate-specific membrane antigen, Sensitivity

Read this article at

ScienceOpenPublisher PubMed

Bookmark

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Positron emission tomography (PET) of 68Ga-labelled prostate-specific membrane antigen (68Ga-PSMA) is an emerging imaging modality introduced to assess the burden of prostate cancer, typically in biochemically recurrent or advanced disease. 68Ga-PSMA PET provides the ability to selectively identify and localize metastatic prostate cancer cells and subsequently change patient management. Owing to its limited history, robust sensitivity and specificity data are not available for 68Ga-PSMA PET-positive scans.