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      Pharmacological preconditioning with low-dose cyclosporine or FK506 reduces subsequent ischemia/reperfusion injury in rat kidney.

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      Journal: Transplantation
      Publisher: Ovid Technologies (Wolters Kluwer Health)

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          Abstract

          Ischemia/reperfusion (I/R) injury in the early posttransplant period is closely associated with delayed recovery of graft function, increased acute rejection, and late allograft dysfunction. Pharmacological preconditioning with low-dose cyclosporine (CsA) or FK506 was performed to induce ischemic tolerance in rat kidney with I/R injury.

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          PubMed ID:: 11740384
          DOI:: 10.1097/00007890-200112150-00008

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