Electrocardiographic Preexcitation and Risk of Cardiovascular Morbidity and Mortality

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Abstract

<p class="first" id="d15838459e158">The majority of available data on the clinical course of patients with ventricular preexcitation in the ECG originates from tertiary centers. We aimed to investigate long-term outcomes in individuals from a primary care population with electrocardiographic preexcitation. </p>

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Most cited references 24

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Validity of the diagnoses atrial fibrillation and atrial flutter in a Danish patient registry.

Albert M Joensen, Sam Riahi, Thomas Rix … (2012)

To assess the validity of the diagnoses of atrial fibrillation (AF) and atrial flutter (AFL) for men and women recorded in the Danish National Patient Registry, and to assess the relative distribution of AF and AFL. Review of medical records for incident cases of AF and/or AFL in the Diet, Cancer, and Health cohort study. Participants were enrolled in 1993-97 with 13.6 years of follow-up until 30 December, 2009. The positive predictive value of the combined diagnosis of AF and/or AFL was 92.6% (95% CI 88.8%; 95.2%) with no significant difference between sexes (men 93.7% (133/142), women 90.8% (129/142)). The proportion of AFL either alone or in combination with AF was significantly higher in men than in women (13.5% (18/133) vs. 5.4% (7/129), p =0.03). The positive predictive value of the specified diagnosis of AFL was 57.5% for men (46/80) and 29.6% for women (8/27). This study shows that the validity of the diagnosis of AF and/or AFL is high and may be used for registry-based studies. A specified diagnosis of AFL was rarely used and was not reliable to distinguish between cases of AF and AFL.

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Ventricular fibrillation in the Wolff-Parkinson-White syndrome.

Stuart Gallagher, D E Sellers, Sebastian G Klein … (1979)

To examine the risk of ventricular fibrillation in patients with the Wolff-Parkinson-White syndrome, we compared patients who had this syndrome and a history of ventricular fibrillation related to preexcitation with patients who had the syndrome without this history. Ventricular fibrillation occurred during atrial fibrillation, with rapid conduction over the accessory pathway, and these patients had a higher prevalence of both reciprocating tachycardia and atrial fibrillation (14 of 25 vs. 18 of 73, P = 0.004) and multiple accessory pathways (five of 25 vs. four of 73, P = 0.012). The shortest preexcitation R-R interval during atrial fibrillation was less in the group with ventricular fibrillation (mean shortest R-R, 180 vs. 240 milliseconds, P less than 0.0001) as was the average R-R interval (mean average R-R, 269 vs 340 milliseconds, P less than 0.0001). Patients with Wolff-Parkinson-White syndrome who are most susceptible to ventricular fibrillation have a history of atrial fibrillation and reciprocating tachycardia, demonstrate rapid conduction over an accessory pathway during atrial fibrillation and have multiple accessory pathways.

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J-shaped association between QTc interval duration and the risk of atrial fibrillation: results from the Copenhagen ECG study.

Jonas Nielsen, Claus Graff, Adrian Pietersen … (2013)

The aim of this study was to investigate whether the heart rate-corrected QT (QTc) interval on the electrocardiogram (ECG) is associated with the onset of atrial fibrillation (AF).

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Author and article information

Journal

Title: Circulation: Arrhythmia and Electrophysiology

Abbreviated Title: Circ Arrhythm Electrophysiol

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Print): 1941-3149

ISSN (Electronic): 1941-3084

Publication date Created: June 2017

Publication date (Print): June 2017

Volume: 10

Issue: 6

Affiliations

[1 ]From the Laboratory for Molecular Cardiology, The Heart Centre, Rigshospitalet, Copenhagen, Denmark (M.W.S., P.V.R., J.G., M.S.O., S.H., J.H.S., A.G.H., J.B.N.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (S.H., L.K., J.H.S.); Department of Health Science and Technology, Aalborg University, Denmark (S.M.H., C.G., C.T.-P.); Copenhagen General Practitioners’ Laboratory, Denmark (A.P.); and Division of Cardiovascular Medicine, Department...

Article

DOI: 10.1161/CIRCEP.116.004778

PubMed ID: 28576781

SO-VID: ef6fb178-f493-4819-9ffa-cc9290b8fb5b

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Electrocardiographic Preexcitation and Risk of Cardiovascular Morbidity and Mortality : Results From the Copenhagen ECG Study

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Abstract

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Cardiovascular Innovations and Applications

Most cited references 24

Validity of the diagnoses atrial fibrillation and atrial flutter in a Danish patient registry.

Ventricular fibrillation in the Wolff-Parkinson-White syndrome.

J-shaped association between QTc interval duration and the risk of atrial fibrillation: results from the Copenhagen ECG study.

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