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      Hyposthenuria: Sándor Korányi’s Concept of Renal Insufficiency

      American Journal of Nephrology

      S. Karger AG

      Renal insufficiency, Korányi, Urine, Freezing point depression

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          Abstract

          Around the turn of the 19th century, the Hungarian physiologist and clinician, Sándor Korányi, started to use physicochemical methods to estimate renal function. In parallel with the deterioration of renal function, he found characteristic changes in the freezing point depression of urine, which he termed hyposthenuria. On the basis of these findings, he was the first to introduce the functional concept of renal insufficiency.

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          Author and article information

          Journal
          AJN
          Am J Nephrol
          10.1159/issn.0250-8095
          American Journal of Nephrology
          S. Karger AG
          978-3-8055-6855-5
          978-3-318-00128-0
          0250-8095
          1421-9670
          1999
          April 1999
          23 April 1999
          : 19
          : 2
          : 320-322
          Affiliations
          First Department of Medicine, Albert Szent-Györgyi Medical University, Szeged, Hungary
          Article
          13468 Am J Nephrol 1999;19:320–322
          10.1159/000013468
          10213835
          © 1999 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Figures: 1, Tables: 1, References: 9, Pages: 3
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/13468
          Categories
          Origins of Nephrology – The Modern Era

          Cardiovascular Medicine, Nephrology

          Renal insufficiency, Korányi, Freezing point depression, Urine

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