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      Associations between resting-state functional connectivity and treatment response in a randomized clinical trial for posttraumatic stress disorder.

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          Abstract

          Alterations in resting-state functional connectivity (rsFC) have been reported in posttraumatic stress disorder (PTSD). Here, we examined pre- and post-treatment rsFC during a randomized clinical trial to characterize alterations and examine predictors of treatment response.

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          Author and article information

          Journal
          Depress Anxiety
          Depression and anxiety
          Wiley
          1520-6394
          1091-4269
          October 2020
          : 37
          : 10
          Affiliations
          [1 ] Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan.
          [2 ] Department of Psychiatry, University of Michigan, Ann Arbor, Michigan.
          [3 ] Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, Ohio.
          [4 ] Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
          [5 ] Department of Psychiatry, New York University Medical School, New York, New York.
          [6 ] Mental Health Service Line, Atlanta VA Healthcare System, Decatur, Georgia.
          [7 ] Department of Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, Georgia.
          Article
          NIHMS1620429
          10.1002/da.23075
          7722156
          32668087
          efa7cf97-3025-4fac-aee9-1a72fdbdbb6e
          Published 2020. This article is a U.S. Government work and is in the public domain in the USA.

          PTSD,fMRI,functional connectivity,prolonged exposure,resting state,sertraline

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