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      Immunological Study on Metabolic Changes in Childhood

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      Journal of Vascular Research

      S. Karger AG

      Arteriosclerosis, Antibody, Childhood

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          Abstract

          A total number of 219 children from three different regions (low land, hill and mountain country) was examined for the presence of antibodies to a panel of antigens used in studies of atherosclerosis. The average percentage of antibodies found in an unselected group of children aged from 6 to 15 years was 31. This finding would assume the abnormal metabolic defect already in the first and second age decades, accompanied by a subsequent formation of antibodies. The authors discuss its causes and assume that the defect is reversible and can be influenced by a later way of life. The complement consumption test was used as a method of examination.

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          Author and article information

          Journal
          JVR
          J Vasc Res
          10.1159/issn.1018-1172
          Journal of Vascular Research
          S. Karger AG
          1018-1172
          1423-0135
          1970
          1970
          18 September 2008
          : 7
          : 1
          : 44-50
          Affiliations
          Institute of Hematology and Blood Transfusion (Director: Prof. Dr. J. Hořejší) and IVth Clinic of Paediatrics, Faculty of General Medicine, Charles University, Prague (Head: Prof. Dr. F. Blažek)
          Article
          157815 Angiologica 1970;7:44–50
          10.1159/000157815
          © 1970 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 7
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