Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial.

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Abstract

Compared with open resection, laparoscopic resection of rectal cancers is associated with improved short-term outcomes, but high-level evidence showing similar long-term outcomes is scarce. We aimed to compare survival outcomes of laparoscopic surgery with open surgery for patients with mid-rectal or low-rectal cancer.

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Author and article information

Journal

Journal ID (iso-abbrev): Lancet Oncol.

Title: The Lancet. Oncology

ISSN (Electronic): 1474-5488

ISSN (Print): 1470-2045

Publication date (Electronic): Jun 2014

Volume: 15

Issue: 7

Affiliations

[1 ] Department of Surgery, Seoul National University College of Medicine, Colorectal Cancer Center, Seoul National University Cancer Hospital, Seoul, South Korea; Cancer Research Institute, Seoul National University, Seoul, South Korea.

[2 ] Biometric Research Branch, Division of Cancer Epidemiology and Prevention, Research Institute and Hospital, National Cancer Center, Goyang, South Korea.

[3 ] Department of Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

[4 ] Department of Colon and Rectal Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

[5 ] Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, South Korea.

[6 ] Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

[7 ] Division of Medical Oncology and Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.

[8 ] Department of Pathology, Seoul National University Hospital, Seoul, South Korea.

[9 ] Department of Radiation Oncology, Seoul National University Hospital, Seoul, South Korea.

[10 ] Department of Radiation Oncology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

[11 ] Department of Pathology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

[12 ] Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

[13 ] Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Goyang, South Korea. Electronic address: jayoh@ncc.re.kr.

Article

Publisher Item ID: S1470-2045(14)70205-0

DOI: 10.1016/S1470-2045(14)70205-0

PubMed ID: 24837215

SO-VID: efe5437b-f75d-41f5-9146-9b47e391e18b

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