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<h5 class="section-title" id="d701986e138">Introduction:</h5>
<p id="P1">Electronic cigarettes (e-cigarettes) are promoted as a less risky
alternative to conventional cigarettes and have grown in popularity.
Experimental and clinical evidence suggests that they could increase the
risk of myocardial infarction.
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<h5 class="section-title" id="d701986e143">Methods:</h5>
<p id="P2">The National Health Interview Surveys of 2014
(
<i>n</i>=36,697) and 2016 (
<i>n</i>=33,028) were used
to examine the cross-sectional association between e-cigarette use (never,
former, some days, daily) and cigarette smoking (same categories) and
myocardial infarction in a single logistic regression model that also
included demographics (age, gender, BMI) and health characteristics
(hypertension, diabetes, and hypercholesterolemia) using logistic
regression. Data were collected in 2014 and 2016 and analyzed in 2017 and
2018.
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<h5 class="section-title" id="d701986e154">Results:</h5>
<p id="P3">Daily e-cigarette use was independently associated with increased
odds of having had a myocardial infarction (OR=1.79, 95% CI=1.20, 2.66,
p=0.004) as was daily conventional cigarette smoking (OR=2.72, 95% CI=2.29,
3.24,
<i>p</i><0.001). Former and some day e-cigarette use
were not significantly associated with having had a myocardial infarction
(
<i>p</i>=0.608 and
<i>p</i>=0.392) whereas former
(OR=1.70,
<i>p</i><0.001) and some day cigarette smoking
(OR=2.36,
<i>p</i><0.001) were. Odds of a myocardial
infarction were also increased with history of hypertension (OR=2.32,
<i>p</i><0.001); high cholesterol (OR=2.36,
<i>p</i><0.001); and diabetes (OR=1.77,
<i>p</i><0.001); and age (OR=1.65 per 10 years,
<i>p</i><0.001). Women (OR=0.47,
<i>p</i><0.001) had lower odds of myocardial
infarction.
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<h5 class="section-title" id="d701986e190">Conclusions:</h5>
<p id="P4">Daily e-cigarette use, adjusted for smoking conventional cigarettes
as well as other risk factors, is associated with increased risk of
myocardial infarction.
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