The influence of porosity on the hemocompatibility of polyhedral oligomeric silsesquioxane poly (caprolactone-urea) urethane

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

The physio-chemical properties of blood contacting biomaterials play an important role in determining their hemocompatibility. It is shown in literature that surface roughness and porosity have significant effect on hemocompatibility. In this study, we use a biocompatible, low thrombogenic nanocomposite polymer called POSS-PCU to test this hypothesis: would porosity compromise the hemocompatibility of POSS-PCU. We compared the hemocompatibility of POSS-PCU films of various pore sizes with PTFE, which is a commercially available material used in most blood contacting devices.

Related collections

Most cited references 38

Record: found
Abstract: found
Article: not found

Coronary stents: a materials perspective.

Devang Patel, Ramesh G. Mani, Satish C. Agrawal … (2007)

The objective of this review is to describe the suitability of different biomaterials as coronary stents. This review focuses on the following topics: (1) different materials used for stents, (2) surface characteristics that influence stent-biology interactions, (3) the use of polymers in stents, and (4) drug-eluting stents, especially those that are commercially available.

0 comments Cited 117 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Thrombus formation in vivo.

Bruce Furie, Barbara C. Furie (2005)

To examine thrombus formation in a living mouse, new technologies involving intravital videomicroscopy have been applied to the analysis of vascular windows to directly visualize arterioles and venules. After vessel wall injury in the microcirculation, thrombus development can be imaged in real time. These systems have been used to explore the role of platelets, blood coagulation proteins, endothelium, and the vessel wall during thrombus formation. The study of biochemistry and cell biology in a living animal offers new understanding of physiology and pathology in complex biologic systems.

0 comments Cited 78 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Contact angle measurement on rough surfaces.

Tammar Meiron, Abraham Marmur, I Saguy (2004)

A new method for the measurement of apparent contact angles at the global energy minimum on real surfaces has been developed. The method consists of vibrating the surface, taking top-view pictures of the drop, monitoring the drop roundness, and calculating the contact angle from the drop diameter and weight. The use of the new method has been demonstrated for various rough surfaces, all having the same surface chemistry. In order to establish the optimal vibration conditions, the proper ranges for the system parameters (i.e., drop volume, vibration time, frequency of vibration, and amplitude of vibration) were determined. The reliability of the method has been demonstrated by the fact that the ideal contact angles of all surfaces, as calculated from the Wenzel equation using the measured apparent contact angles, came out to be practically identical. This ideal contact angle has been compared with three methods of calculation from values of advancing and receding contact angles.