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Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961.
David St Clair
1 ,
Mingqing Xu ,
Peng Wang ,
Yaqin Yu ,
Yourong Fang ,
Feng Zhang ,
Xiaoying Zheng ,
Niufan Gu ,
Guoyin Feng ,
Pak Sham ,
Lin He
Aug 03 2005
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Abstract
Schizophrenia is a common major mental disorder. Intrauterine nutritional deficiency may increase the risk of schizophrenia. The main evidence comes from studies of the 1944-1945 Dutch Hunger Winter when a sharp and time-limited decline in food intake occurred. The most exposed cohort conceived during the famine showed a 2-fold increased risk of schizophrenia.