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      Application of the noise power spectrum in modern diagnostic MDCT: part I. Measurement of noise power spectra and noise equivalent quanta.

      Physics in medicine and biology
      Algorithms, Artifacts, Radiographic Image Enhancement, methods, Radiographic Image Interpretation, Computer-Assisted, Reproducibility of Results, Sensitivity and Specificity, Tomography, X-Ray Computed, instrumentation

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          Abstract

          Dose reduction efforts in diagnostic CT have brought the tradeoff of dose versus image quality to the forefront. The need for meaningful characterization of image noise beyond that offered by pixel standard deviation is becoming increasingly important. This work aims to study the implementation of the noise power spectrum (NPS) and noise equivalent quanta (NEQ) on modern, multislice diagnostic CT scanners. The details of NPS and NEQ measurement are outlined and special attention is paid to issues unique to multislice CT. Aliasing, filter design and effects of acquisition geometry are investigated. While it was found that both metrics can be implemented in modern CT, it was discovered that NEQ cannot be aptly applied with certain non-traditional reconstruction filters or in helical mode. NPS and NEQ under a variety of conditions are examined. Extensions of NPS and NEQ to uses in protocol standardization are also discussed.

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