3
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Organocatalytic Activation of Alkylacetic Esters as Enolate Precursors to React with α,β-Unsaturated Imines

      , , , , , , ,
      Organic Letters
      American Chemical Society (ACS)

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Asymmetric functionalization of alkylacetic esters and their derivatives is traditionally achieved via preformed enolates with chiral auxiliaries. Catalytic versions of such transformations are attractive but challenging. A direct catalytic activation of simple alkylacetic esters via N-heterocyclic carbene organocatalysts to generate chiral enolate intermediates for highly enantioselective reactions is reported.

          Related collections

          Author and article information

          Journal
          Organic Letters
          Org. Lett.
          American Chemical Society (ACS)
          1523-7060
          1523-7052
          September 24 2013
          September 26 2013
          : 15
          : 19
          : 4956-4959
          Article
          10.1021/ol4021805
          24070158
          f0b4dff8-d990-4beb-b4a4-20bb8034c716
          © 2013
          History

          Comments

          Comment on this article