Blog
About

171
views
0
recommends
+1 Recommend
0 collections
    12
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Mechanisms and Functional Implications of Adult Neurogenesis

      , ,

      Cell

      Elsevier BV

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The generation of new neurons is sustained throughout adulthood in the mammalian brain due to the proliferation and differentiation of adult neural stem cells. In this review, we discuss the factors that regulate proliferation and fate determination of adult neural stem cells and describe recent studies concerning the integration of newborn neurons into the existing neural circuitry. We further address the potential significance of adult neurogenesis in memory, depression, and neurodegenerative disorders such as Alzheimer's and Parkinson's disease.

          Related collections

          Author and article information

          Journal
          Cell
          Cell
          Elsevier BV
          00928674
          February 2008
          February 2008
          : 132
          : 4
          : 645-660
          10.1016/j.cell.2008.01.033
          18295581
          © 2008

          https://www.elsevier.com/tdm/userlicense/1.0/

          https://www.elsevier.com/open-access/userlicense/1.0/

          Comments

          Comment on this article