Prosthodontics represents a highly developed body of knowledge and skill that spans multiple disciplines. Numerous studies can be cited that address biologic, mechanical, or materials science factors that influence decisions about patient care. On a daily basis as clinicians, teachers, or patients, we experience an interplay of social, economic, and psychologic conditions that similarly influence treatment decisions. This article explored a rationale for including a clear, explicit emphasis on knowledge and skill development for prosthodontic practice and education related to social, psychologic, and economic factors.