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      A systematic review on the effect of aspirin in the prevention of post-operative arterial thrombosis in patients undergoing total hip and total knee arthroplasty.

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          Abstract

          Major surgery is associated with increased risk of venous thromboembolism (VTE), which is decreased by anticoagulant drugs. Evidence is growing that major surgery is associated with increased risk of arterial thrombosis (AT). With the aim of testing aspirin ability in reducing the risk of post-operative AT, we performed a systematic review of studies in which acetylsalicylic acid (ASA) was compared to anticoagulant drugs in VTE prophylaxis of patients undergoing total hip replacement (THR) or total knee replacement (TKR).

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          Author and article information

          Journal
          Thromb. Res.
          Thrombosis research
          1879-2472
          0049-3848
          Sep 2014
          : 134
          : 3
          Affiliations
          [1 ] Haematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy; Medicina III, Azienda Ospedaliera San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy.
          [2 ] Medicina 1, Ospedale di Circolo Varese, Varese, Italy.
          [3 ] Medicina III, Azienda Ospedaliera San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy. Electronic address: marco.cattaneo@unimi.it.
          Article
          S0049-3848(14)00353-3
          10.1016/j.thromres.2014.06.027
          25064034
          f14f9506-e03c-4e66-88ed-4129aab667a6
          Copyright © 2014 Elsevier Ltd. All rights reserved.
          History

          Antiplatelet agents,Arterial thrombosis,Orthopedics,Venous thrombosis

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