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      Multilocus sequence typing implicates rodents as the main reservoir host of human-pathogenic Borrelia garinii in Japan.

      Journal of Clinical Microbiology
      Animals, Bacterial Typing Techniques, Borrelia burgdorferi Group, classification, genetics, isolation & purification, Cluster Analysis, DNA, Bacterial, chemistry, Disease Reservoirs, Genotype, Humans, Japan, Lyme Disease, microbiology, Molecular Sequence Data, Multilocus Sequence Typing, Phylogeny, Rodentia, Sequence Analysis, DNA, Ticks

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          Abstract

          Multilocus sequence typing of Borrelia garinii isolates from humans and comparison with rodent and tick isolates were performed. Fifty-nine isolates were divided into two phylogenetic groups, and an association was detected between clinical and rodent isolates, suggesting that, in Japan, human-pathogenic B. garinii comes from rodents via ticks.

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