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      Progress and problems with the use of viral vectors for gene therapy.

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          Abstract

          Gene therapy has a history of controversy. Encouraging results are starting to emerge from the clinic, but questions are still being asked about the safety of this new molecular medicine. With the development of a leukaemia-like syndrome in two of the small number of patients that have been cured of a disease by gene therapy, it is timely to contemplate how far this technology has come, and how far it still has to go.

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          Author and article information

          Journal
          Nat Rev Genet
          Nature reviews. Genetics
          Springer Science and Business Media LLC
          1471-0056
          1471-0056
          May 2003
          : 4
          : 5
          Affiliations
          [1 ] Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA.
          Article
          nrg1066
          10.1038/nrg1066
          12728277
          f1594658-b494-434e-b03d-0ead34c2e754

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