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      Anxiety symptoms and associated functional impairment in children with CHD in a neurodevelopmental follow-up clinic

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          Abstract

          Objectives:

          To examine the prevalence of anxiety symptoms and associated functional impairment to adaptive skills among elementary-aged children with CHD and to determine the need for anxiety screening in this high-risk population.

          Study design:

          In a single-centre retrospective, cohort design, caregivers reported anxiety symptoms using Conner’s scales and functional impairment to adaptive skills using the Adaptive Behavior Assessment System. A total of 194 children were stratified across two cohorts: early elementary (ages 3–6 years) and late elementary (ages 6–14 years). Descriptive statistics summarised the frequency of anxiety symptoms and functional impairment. Spearman’s correlations compared anxiety symptoms to functional impairment of adaptive functioning. Univariable logistic regressions examined demographic and clinical characteristics associated with anxiety symptoms.

          Results:

          The majority of patients presented with anxiety, early elementary (63%), and late elementary cohorts (78%). Functional impairment was moderately correlated with anxiety symptoms in the early elementary cohort ( r s = −.42, 95% CI [−0.58, −0.21], p = <.001). Greater anxiety symptoms were associated with lower cardiac complexity at primary age of surgery in the late elementary cohort (OR = 12.15, p = 0.019). Lesser anxiety symptoms were associated with having private insurance (OR = 0.25, p = 0.014).

          Conclusion:

          This study demonstrates anxiety symptoms are common and associated with functional impairment to adaptive functioning in younger children with CHD. No clear clinical predictors exist for anxiety symptoms or functional impairment; therefore, screening for anxiety symptoms may need to be added to standard clinical assessment of all children with CHD participating in neurodevelopmental follow-up.

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          Most cited references32

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          Correlation Coefficients

          Correlation in the broadest sense is a measure of an association between variables. In correlated data, the change in the magnitude of 1 variable is associated with a change in the magnitude of another variable, either in the same (positive correlation) or in the opposite (negative correlation) direction. Most often, the term correlation is used in the context of a linear relationship between 2 continuous variables and expressed as Pearson product-moment correlation. The Pearson correlation coefficient is typically used for jointly normally distributed data (data that follow a bivariate normal distribution). For nonnormally distributed continuous data, for ordinal data, or for data with relevant outliers, a Spearman rank correlation can be used as a measure of a monotonic association. Both correlation coefficients are scaled such that they range from -1 to +1, where 0 indicates that there is no linear or monotonic association, and the relationship gets stronger and ultimately approaches a straight line (Pearson correlation) or a constantly increasing or decreasing curve (Spearman correlation) as the coefficient approaches an absolute value of 1. Hypothesis tests and confidence intervals can be used to address the statistical significance of the results and to estimate the strength of the relationship in the population from which the data were sampled. The aim of this tutorial is to guide researchers and clinicians in the appropriate use and interpretation of correlation coefficients.
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            The incidence of congenital heart disease

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              Prevalence and Treatment of Depression, Anxiety, and Conduct Problems in US Children

              To use the latest data to estimate the prevalence and correlates of currently diagnosed depression, anxiety problems, and behavioral or conduct problems among children, and the receipt of related mental health treatment.
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                Author and article information

                Journal
                9200019
                21021
                Cardiol Young
                Cardiol Young
                Cardiology in the young
                1047-9511
                1467-1107
                1 December 2023
                June 2023
                20 June 2022
                20 December 2023
                : 33
                : 6
                : 864-871
                Affiliations
                [1 ]Department of Pediatrics, Division of General Pediatrics, University of Utah, Salt Lake City, UT, USA;
                [2 ]Department of Pediatrics, Division of Developmental and Behavioral Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA;
                [3 ]Department of Cardiology, Pediatrics, Maine Medical Center, Portland, ME, USA;
                [4 ]Department of Internal Medicine, Division of Epidemiology, University of Utah, Salt Lake City, UT, USA
                [5 ]Department of Pediatrics, Division of Critical Care Medicine, University of Utah, Salt Lake City, UT, USA
                Author notes
                Author for correspondence: Sean Cunningham, PhD, University of Utah School of Medicine, Department of Pediatrics, P.O. Box 581289, Salt Lake City, UT 84158, USA. Tel: +801 587 2255; Fax: +801 585 2209. Sean.Cunningham@ 123456hsc.utah.edu
                Author information
                http://orcid.org/0000-0002-5547-5666
                http://orcid.org/0000-0003-0923-8659
                Article
                NIHMS1948376
                10.1017/S1047951122001767
                10704710
                35723019
                f1e0a916-5e13-4ae7-9cfd-27b8141284a7

                This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.

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                congenital health disease,anxiety,children,cohort study
                congenital health disease, anxiety, children, cohort study

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