Exposure to Gestational Diabetes Is a Stronger Predictor of Dysmetabolic Traits in Children Than Size at Birth.

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Abstract

Being born small or large for gestational age and intrauterine exposure to gestational diabetes (GDM) increase the risk of type 2 diabetes in the offspring. However, the potential combined deleterious effects of size at birth and GDM exposure remains unknown. We examined the independent effect of size at birth and the influence of GDM exposure in utero on cardiometabolic traits, body composition, and puberty status in children.

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Journal

Journal ID (iso-abbrev): J Clin Endocrinol Metab

Title: The Journal of clinical endocrinology and metabolism

Publisher: The Endocrine Society

ISSN (Electronic): 1945-7197

ISSN (Print): 0021-972X

Publication date (Electronic): May 01 2019

Volume: 104

Issue: 5

Affiliations

[1 ] Division for Diet, Disease Prevention and Toxicology, National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.

[2 ] Department of Endocrinology, Diabetes and Bone-Metabolic Research Unit, Rigshospitalet, Copenhagen, Denmark.

[3 ] The Danish Diabetes Academy, Odense, Denmark.

[4 ] Centre for Foetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.

[5 ] Vitality - Centre for Good Older Lives, Department of Nutrition, Sports and Exercise, University of Copenhagen, Copenhagen, Denmark.

Article

Publisher Item ID: 5230930

DOI: 10.1210/jc.2018-02044

PubMed ID: 30521046

SO-VID: f1e29f08-ca7e-4111-a6f5-069718b2613b

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