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      Urinary Tract Infections in the Infant

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          Abstract

          Urinary tract infection (UTI) in an infant may be the first indication of an underlying renal disorder. Early recognition and initiation of adequate therapy for UTI is important to reduce the risk of long-term renal scarring. Ampicillin and gentamicin are traditionally the empiric treatment of choice; however, local antibiotic resistance patterns should be considered. Maternal antibiotics during pregnancy also increase the risk of resistant pathogens during neonatal UTI. Long-term management after the first UTI in infants remains controversial because of lack of specific studies in this age group and the risk-benefit issues for antibiotic prophylaxis between reduced recurrent disease and emergent antibiotic resistance.

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          Author and article information

          Journal
          7501306
          3055
          Clin Perinatol
          Clin Perinatol
          Clinics in perinatology
          0095-5108
          1557-9840
          20 April 2017
          24 December 2014
          March 2015
          16 July 2017
          : 42
          : 1
          : 17-vii
          Affiliations
          Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA
          Author notes
          [* ] Corresponding author. patrick.seed@ 123456duke.edu
          Article
          PMC5511626 PMC5511626 5511626 nihpa866358
          10.1016/j.clp.2014.10.003
          5511626
          25677994
          f1eb98d3-3d20-4d58-b238-78b25aa167ce
          History
          Categories
          Article

          Urinary tract infection,Vesicoureteral reflux,Antibiotic resistance,Renal imaging, Escherichia coli ,Infants

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