Micronutrient Intake and the Presence of the Metabolic Syndrome

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Background:

Dietary micronutrients have been proposed to protect against oxidative damage and related clinical complications.

Aims:

We aimed to compare the micronutrient intake between individuals with and without metabolic syndrome (MS).

Materials and Methods:

This cross-sectional study included 3800 men and women who were aged between 35 and 65 years. The diagnosis of the MS was based on International Diabetes Federation criteria. Dietary intake of participants was assessed using a questionnaire for 24 h dietary recall. Student's t-test and Mann–Whitney U-tests were used for comparing the micronutrient intake of subjects with or without the MS and the odds ratio for the presence of the MS was calculated for each micronutrient by control for total energy intake adjusted by the residue method.

Results:

The mean age of MS subjects and the control group was 48.8 ± 7.9 years and 47.6 ± 7.6 years, respectively. Energy-adjusted intake of vitamin E ( P < 0.05), B2 ( P < 0.01), and B12 ( P < 0.05) was higher in normal women compared with women with MS. Energy-adjusted intake of vitamin B1 was significantly higher in women with MS. After logistic regression analysis, no significant association between micronutrient intake and MS was shown.

Conclusion:

We found no significant association between micronutrient intake and MS.

Related collections

Most cited references 31

Record: found
Abstract: found
Article: not found

The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey.

E. Ford, A. H. Mokdad, W Giles … (2003)

Oxidative stress may play a role in the pathophysiology of diabetes and cardiovascular disease, but little is known about antioxidant status among individuals with the metabolic syndrome who are at high risk for developing these conditions. Using data from the Third National Health and Nutrition Examination Survey (1988-1994), we compared circulating concentrations of vitamins A, C, and E; retinyl esters; five carotenoids; and selenium in 8,808 U.S. adults aged > or = 20 years with and without the metabolic syndrome. After adjusting for age, sex, race or ethnicity, education, smoking status, cotinine concentration, physical activity, fruit and vegetable intake, and vitamin or mineral use, participants with the metabolic syndrome had significantly lower concentrations of retinyl esters, vitamin C, and carotenoids, except lycopene. With additional adjustment for serum lipid concentrations, vitamin E concentrations were significantly lower in participants with the metabolic syndrome than those without the syndrome. Retinol concentrations were similar between the two groups. After excluding participants with diabetes, the results were very similar. Consumption of fruits and vegetables was also lower among people with the metabolic syndrome. Adults with the metabolic syndrome have suboptimal concentrations of several antioxidants, which may partially explain their increased risk for diabetes and cardiovascular disease.

0 comments Cited 116 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Major dietary patterns in relation to general obesity and central adiposity among Iranian women.

Ahmad Esmaillzadeh, Leila Azadbakht (2008)

Studying the links between dietary patterns and obesity is especially relevant for Middle-Eastern populations because of their high prevalence of a particular type of obesity, the so-called Middle-Eastern pattern, and their diets' unique characteristics. Therefore, we wondered if major dietary patterns are related to the prevalence of general obesity and central adiposity among Iranian women. In this cross-sectional study of 486 women aged 40-60 y, usual dietary intakes were evaluated using a FFQ and anthropometric measurements. By the use of factor analysis, we extracted 3 major dietary patterns: healthy dietary pattern, western dietary pattern, and Iranian dietary pattern. Individuals in the upper category of the healthy pattern score were less likely to be generally (OR = 0.28; 95% CI = 0.14-0.53) and centrally obese (OR = 0.30; 95% CI = 0.16-0.55), whereas those in the upper quintile of western pattern had greater odds (for general obesity: 2.73; 95% CI = 1.46-5.08 and for central obesity: 5.74; 95% CI =2.99-10.99). Controlling for potential confounders attenuated the associations, but even after adjusting for energy intake, the associations were significant for both general and central obesity. Although the Iranian dietary pattern and general obesity were not significantly associated, subjects in the highest quintile had greater odds of being centrally obese, either before (OR = 2.15; 95% CI = 1.18-3.90) or after (OR = 2.08; 95% CI = 1.09-3.65) control for confounders. This study indicates significant associations among major dietary patterns, general obesity, and central adiposity in a Middle-Eastern country. Further prospective investigations are required to confirm such associations.

0 comments Cited 107 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.

B N AMES (2006)

Inadequate dietary intakes of vitamins and minerals are widespread, most likely due to excessive consumption of energy-rich, micronutrient-poor, refined food. Inadequate intakes may result in chronic metabolic disruption, including mitochondrial decay. Deficiencies in many micronutrients cause DNA damage, such as chromosome breaks, in cultured human cells or in vivo. Some of these deficiencies also cause mitochondrial decay with oxidant leakage and cellular aging and are associated with late onset diseases such as cancer. I propose DNA damage and late onset disease are consequences of a triage allocation response to micronutrient scarcity. Episodic shortages of micronutrients were common during evolution. Natural selection favors short-term survival at the expense of long-term health. I hypothesize that short-term survival was achieved by allocating scarce micronutrients by triage, in part through an adjustment of the binding affinity of proteins for required micronutrients. If this hypothesis is correct, micronutrient deficiencies that trigger the triage response would accelerate cancer, aging, and neural decay but would leave critical metabolic functions, such as ATP production, intact. Evidence that micronutrient malnutrition increases late onset diseases, such as cancer, is discussed. A multivitamin-mineral supplement is one low-cost way to ensure intake of the Recommended Dietary Allowance of micronutrients throughout life.

0 comments Cited 100 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Journal

Journal ID (nlm-ta): N Am J Med Sci

Journal ID (iso-abbrev): N Am J Med Sci

Journal ID (publisher-id): NAJMS

Title: North American Journal of Medical Sciences

Publisher: Medknow Publications & Media Pvt Ltd (India )

ISSN (Print): 2250-1541

ISSN (Electronic): 1947-2714

Publication date (Print): June 2013

Volume: 5

Issue: 6

Pages: 377-385

Affiliations

[1] Biochemistry of Nutrition Research Center and department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

[1 ] Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran

[2 ] Brighton and Sussex Medical School, Division of Medical Education, Mayfield House, University of Brighton, BN1 9PH, UK

Author notes

Address for correspondence: Dr. Majid Ghayour-Mobarhan, Cardiovascular Research Center, Mashhad University of Medical Science, Mashhad, Iran. E-mail: ghayourm@ 123456mums.ac.ir

Article

Publisher ID: NAJMS-5-377

DOI: 10.4103/1947-2714.114171

PMC ID: 3731870

PubMed ID: 23923113

SO-VID: f2162b4a-53d3-41e3-bff8-e6b0cabff0e3

License:

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Micronutrient Intake and the Presence of the Metabolic Syndrome

Read this article at

Abstract

Background:

Aims:

Materials and Methods:

Results:

Conclusion:

Related collections

Karger: Nutrition and Dietetics

Most cited references 31

The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey.

Major dietary patterns in relation to general obesity and central adiposity among Iranian women.

Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.

Author and article information

Journal

Affiliations

Author notes

Article

History

Categories

Comments

Comment on this article

Similar content 290

Cited by 22

Most referenced authors 529