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      Follicle-stimulating hormone measured in unextracted urine: a reliable tool for easy assessment of ovarian capacity

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      Fertility and Sterility
      Elsevier BV

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          Abstract

          To determine the presence of FSH in unextracted urine of perimenopausal women using a microparticle enzyme immunoassay kit on an AxSYM random access immunoassay analyzer. Controlled descriptive study. A large teaching hospital and infertility clinic. Forty perimenopausal women aged 32-55 years admitted to our clinic for a gynecological operation. None. Mean serum FSH level and urinary FSH in early-morning urine, in a random void urine sample, and in 24-hour urine on the same day. FSH in urine on the day of excretion and 1 and 4 weeks thereafter, stored under various conditions. FSH in urine before and after extraction. The Pearson's correlation coefficient between mean serum FSH levels and urinary FSH in early morning urine was 0.904, in a random void 0.915, and in 24-hour urine 0.857. Determination of optimal storage conditions revealed that urine was best kept at 4 degrees C without any additive. The correlation between FSH in extracted and unextracted urine was 98.9%. In perimenopausal women, FSH can be reliably measured in unextracted urine. The correlation between urinary FSH and a random void urine sample and mean FSH from a serial serum sample is very high. Urine can be stored for 4 weeks at 4 degrees C without loss of FSH immunoreactivity.

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          Author and article information

          Journal
          Fertility and Sterility
          Fertility and Sterility
          Elsevier BV
          00150282
          September 1998
          September 1998
          : 70
          : 3
          : 544-548
          Article
          10.1016/S0015-0282(98)00201-5
          9757888
          f2284356-72f2-423a-8dc4-e0d4b62122c1
          © 1998

          https://www.elsevier.com/tdm/userlicense/1.0/

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