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      Akt1 in endothelial cell and angiogenesis.

      Cell Cycle

      Signal Transduction, Endothelial Cells, metabolism, Neovascularization, Physiologic, Phosphorylation, Protein Isoforms, Proto-Oncogene Proteins c-akt, Animals

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          Abstract

          Akt, also known as Protein kinase B (PKB), regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Akt influences the expression and/or activity of various pro- and anti-angiogenic factors and Akt isoforms (Akt1, Akt2 and Akt3) have been proposed as therapeutic targets for angiogenesis-related anomalies such as cancer and ischemic injury.

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          16552185
          1569947

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