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      The Influence of Preexisting Vascular Disease on the Outcome of Renal Transplantation in Diabetic Patients

      Nephron

      S. Karger AG

      Renal transplantation, Diabetes mellitus, Vascular complications

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          Abstract

          We analyzed the impact of prior vascular disease on the outcome of renal transplantation in 99 insulin-dependent diabetic patients. Thirty-three patients (group A) had clinical evidence of vascular disease prior to renal transplantation and 66 patients (group B) had no clinical vascular events in the pretransplant period. The median follow-up in group A patients was 14 months and in group B it was 23 months. The group A patients with preexisting vascular disease had a significant increase in mortality (33%) compared to group B (11%) (A vs. B; p = 0.01). The rate of graft loss was not significantly different between the two groups (45 vs. 42%; p = 0.94). Our data suggest that preexisting clinical vascular disease has a significant negative effect on patient survival in diabetic recipients of cadaver kidney transplants.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1988
          1988
          09 December 2008
          : 48
          : 1
          : 74-75
          Affiliations
          Department of Medicine, University of Minnesota Medical School and Hennepin County Medical Center, Minneapolis, Minn., USA
          Article
          184883 Nephron 1988;48:74–75
          10.1159/000184883
          3277078
          © 1988 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 2
          Categories
          Short Communication

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