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      Diabetes mellitus referida: incidência e determinantes, em coorte de idosos do município de São Paulo, Brasil, Estudo SABE – Saúde, Bem-Estar e Envelhecimento Translated title: Reported diabetes mellitus: incidence and determinants in cohort of community dwelling elderly people in São Paulo City, Brazil: SABE study, health, wellness and aging

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          Abstract

          Resumo Verificar a associação da incidência de diabetes melito (DM) e variáveis determinantes em coorte de idosos. Foram analisados idosos, participantes do Estudo SABE – Saúde, Bem-Estar e Envelhecimento, realizado no município de São Paulo, em 2000 (2.143 idosos), e em 2006 (1.115 idosos). As variáveis de estudo foram: DM; sociodemográficas (sexo, grupo etário, escolaridade, companhia no domicílio), estado nutricional (risco para obesidade, obesidade e gordura abdominal), clínicas (número de doenças referidas) e de estilo de vida (ingestão de bebida alcoólica, hábito de fumar, ingestão de carnes e de frutas, legumes e verduras). Utilizou-se regressão logística múltipla para verificar a associação entre variáveis de estudo, utilizando o programa Stata/SE 10.0. Em 2006, 914 idosos, sobreviventes de 2000, foram analisados, dos quais 72 constituíram os novos casos de DM (incidência de 7,7/1.000 pessoas-ano). Verificou-se associação (p < 0,000) entre incidência de DM com obesidade corporal (OR = 1,67; IC = 1,00–2,81) e gordura abdominal elevada (OR = 2,32; IC = 1,47-3,67). Concluiu-se que a obesidade corporal e a gordura abdominal elevada foram as variáveis que contribuem para o desenvolvimento da DM em idosos.

          Translated abstract

          Abstract To verify the association between the incidence of DM and predictors, in a cohort of elderly people. Elderly people (≥ 60 y) were analyzed, of both genders, participants of the SABE Survey, carried out in the city of São Paulo, Brazil, in 2000 (n = 2,143) and 2006 (n = 1,115). The study variables were: DM; demographic (gender, age group, education level, companionship in the residence), nutritional status (risk for obesity, body obesity, and high abdominal fat), clinical (number of reported diseases), and lifestyle (alcohol consumption, smoking, intake of meat and fruit and vegetables). Multiple logistic regression (p < 0.05) was used to verify the association between variables of this study, with the statistical software Stata/SE 10.1. In 2006, 914 subjects, survivors of 2000, were analyzed and 72 were identified as new cases of DM (7.7/1.000 person-years). It was found that body obesity (OR = 1.67, CI = 1.00 to 2.81) and high abdominal fat (OR = 2.32, CI = 1.47 to 3.67) were predictors of the incidence of DM in the elderly (p < 0.000). It was concluded that body obesity and abdominal fat are the variables which contribute to the development of DM in the elderly.

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          Diabetes mellitus in older people: position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes.

          Diabetes mellitus is a highly prevalent metabolic condition in ageing societies associated with high levels of morbidity, multiple therapies, and functional deterioration that challenges even the best of health care systems to deliver high-quality, individualized care. Most international clinical guidelines have ignored the often-unique issues of frailty, functional limitation, changes in mental health, and increasing dependency that characterize many aged patients with diabetes. A collaborative Expert Group of the IAGG and EDWPOP and an International Task Force have explored the key issues that affect diabetes in older people using a robust method comprising a Delphi process and an evidence-based review of the literature. Eight domains of interest were initially agreed and discussed: hypoglycemia, therapy, care home diabetes, influence of comorbidities, glucose targets, family/carer perspectives, diabetes education, and patient safety. A set of "consensus" statements was produced in each domain of interest. These form a foundation for future policy development in this area and should influence the clinical behavior and approach of all health professionals engaged in delivering diabetes care to older people. Copyright © 2012 American Medical Directors Association. Published by Elsevier Inc. All rights reserved.
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            Body fat distribution and risk of type 2 diabetes in the general population: are there differences between men and women? The MONICA/KORA Augsburg cohort study.

            It remains controversial whether body mass index (BMI), waist circumference (WC), or waist-hip ratio (WHR) is a better risk predictor of type 2 diabetes. The objective was to examine the sex-specific relevance of WC, WHR, and BMI to the development of type 2 diabetes. The prospective population-based cohort study was based on 3055 men and 2957 women aged 35-74 y who participated in the second (1989-1990) or third (1994-1995) MONICA (Monitoring Trends and Determinants on Cardiovascular Diseases) Augsburg survey. The subjects were free of diabetes at baseline. Hazard ratios (HRs) were estimated from Cox proportional hazards models. During a mean follow-up of 9.2 y, 243 cases of incident type 2 diabetes occurred in men and 158 occurred in women. Multivariable-adjusted HRs across quartiles of BMI were 1.0, 1.37, 2.08, and 4.15 in men and 1.0, 3.77, 4.95, and 10.58 in women; those of WC were 1.0, 1.15, 1.57, and 3.40 in men and 1.0, 3.21, 3.98, and 10.70 in women; those of WHR were 1.0, 1.14, 1.80, and 2.84 in men and 1.0, 0.82, 2.06, and 3.51 in women. In joint analyses, the highest risk was observed in men and women with a high BMI in combination with a high WC and a high WHR. Both overall and abdominal adiposity were strongly related to the development of type 2 diabetes. Because there was an additive effect of overall and abdominal obesity on risk prediction, WC should be measured in addition to BMI to assess the risk of type 2 diabetes in both sexes.
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              Association between adiposity in midlife and older age and risk of diabetes in older adults.

              Adiposity is a well-recognized risk factor for type 2 diabetes among young and middle-aged adults, but the relationship between body composition and type 2 diabetes is not well described among older adults. To examine the relationship between adiposity, changes in adiposity, and risk of incident type 2 diabetes in adults 65 years of age and older. Prospective cohort study (1989-2007) of 4193 men and women 65 years of age and older in the Cardiovascular Health Study. Measures of adiposity were derived from anthropometry and bioelectrical impedance data at baseline and anthropometry repeated 3 years later. Incident diabetes was ascertained based on use of antidiabetic medication or a fasting glucose level of 126 mg/dL or greater. Over median follow-up of 12.4 years (range, 0.9-17.8 years), 339 cases of incident diabetes were ascertained (7.1/1000 person-years). The adjusted hazard ratio (HR) (95% confidence interval [CI]) of type 2 diabetes for participants in the highest quintile of baseline measures compared with those in the lowest was 4.3 (95% CI, 2.9-6.5) for body mass index (BMI [calculated as weight in kilograms divided by height in meters squared]), 3.0 (95% CI, 2.0-4.3) for BMI at 50 years of age, 4.2 (95% CI, 2.8-6.4) for weight, 4.0 (95% CI, 2.6-6.0) for fat mass, 4.2 (95% CI, 2.8-6.2) for waist circumference, 2.4 (95% CI, 1.6-3.5) for waist-hip ratio, and 3.8 (95% CI, 2.6-5.5) for waist-height ratio. However, when stratified by age, participants 75 years of age and older had HRs approximately half as large as those 65 to 74 years of age. Compared with weight-stable participants (+/-2 kg), those who gained the most weight from 50 years of age to baseline (> or = 9 kg), and from baseline to the third follow-up visit (> or = 6 kg), had HRs for type 2 diabetes of 2.8 (95% CI, 1.9-4.3) and 2.0 (95% CI, 1.1-3.7), respectively. Participants with a greater than 10-cm increase in waist size from baseline to the third follow-up visit had an HR of type 2 diabetes of 1.7 (95% CI, 1.1-2.8) compared with those who gained or lost 2 cm or less. Among older adults, overall and central adiposity, and weight gain during middle age and after the age of 65 years are associated with risk of diabetes.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                csc
                Ciência & Saúde Coletiva
                Ciênc. saúde coletiva
                ABRASCO - Associação Brasileira de Saúde Coletiva (Rio de Janeiro, RJ, Brazil )
                1413-8123
                1678-4561
                2018
                : 23
                : 11
                : 3913-3922
                Affiliations
                [1] São Paulo São Paulo orgnameUniversidade de São Paulo orgdiv1Faculdade de Saúde Pública orgdiv2Departamento de Nutrição Brazil manuela@ 123456usp.br
                [2] Presidente Prudente orgnameUniversidade Estadual Paulista orgdiv1Departamento de Educação Física Brazil
                [5] São Paulo São Paulo orgnameUniversidade de São Paulo orgdiv1FSP orgdiv2Departamento de Epidemiologia Brazil
                [3] Ribeirão Preto orgnameUniversidade de São Paulo orgdiv1Faculdade de Medicina de Ribeirão Preto Brazil
                [4] São Paulo São Paulo orgnameUniversidade de São Paulo orgdiv1Escola de Enfermagem orgdiv2Departamento de Enfermagem Médico-Cirúrgica Brazil
                Article
                S1413-81232018001103913
                10.1590/1413-812320182311.13062016
                f2aef43e-e9a9-49a6-86d6-f9c5411df6aa

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 24 November 2016
                : 30 May 2015
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 34, Pages: 10
                Product

                SciELO Public Health


                Incidência,Diabetes melito,Idosos,Predictors,Elderly,Diabetes mellitus,Incidence,Preditores

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